October 2022 CME Activity: Effect of Long-Term Exercise Therapy on Motor Symptoms in Parkinson Disease Patients A Systematic Review and Meta-analysis of Randomized Controlled Trials-Effect of Long-Term Exercise Therapy on Motor Symptoms in Parkinson Disease Patients A Systematic Review and Meta-analysis of Randomized Controlled Trials

Effect of Long-Term Exercise Therapy on Motor Symptoms in Parkinson Disease Patients A Systematic Review and Meta-analysis of Randomized Controlled Trials

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A systematic review and meta-analysis examined the effectiveness of long-term exercise therapy (at least 12 weeks) for patients with Parkinson's disease (PD) and the optimal exercise type and dose for improving motor symptoms. The review included 26 randomized controlled trials with a total of 1243 participants. The results showed that Tai Chi, resistance training, and dance all provided significant improvements in physical function and functional mobility. Tai Chi and dance also resulted in balance benefits. However, walking capacity outcomes did not improve after Tai Chi and resistance training, but did improve after dance. The effect sizes of exercise on these outcomes increased with an increase in the intervention duration or length of each session. Higher benefits of exercise on these outcomes were observed at a frequency of 2 times per week. <br /><br />Overall, long-term exercise therapy was found to be an effective treatment for improving motor symptoms in patients with PD, with dance being identified as an ideal exercise choice. However, it is important to note that the results should be interpreted with caution, as indirect comparisons were made among different exercise interventions. Future trials that directly compare different exercise interventions are needed to provide clearer recommendations on exercise type and dose for patients with PD at different stages of the disease.

Keywords

systematic review

exercise therapy

Parkinson's disease

motor symptoms

Tai Chi

resistance training

dance

physical function

balance benefits

intervention duration