May 2021 MSC Virtual Journal Club-PM&R in the Treatment of Transverse Myelitis, etc

Video Transcription

Video Summary

The first video transcript is a presentation by Nathan Katz, a member of the Education Subcommittee on the Medical Student Council for the AAP. He introduces Alexander Rose, a third-year medical student, who gives a talk on the treatment of transverse myelitis using neuromuscular electrical stimulation. Alexander discusses the background knowledge of transverse myelitis, its unique characteristics, and how it affects the spinal cord. He then explains how neuromuscular electrical stimulation works to retrain muscles and build strength in patients with transverse myelitis. Alexander presents a journal article that discusses the effectiveness of neuromuscular electrical stimulation in improving muscle weakness in adults with advanced diseases. He explains the methodology, results, and limitations of the study. Alexander concludes by highlighting the importance of exercise in rehabilitating transverse myelitis and exploring other potential treatments such as robotic-assisted gait training devices and smart home devices. The second video transcript is a presentation by Angela Nwankwo, a third-year medical student. She discusses a systematic review and meta-analysis of alpha-lipoic acid (ALA) in the treatment of diabetic peripheral neuropathy. Angela provides an overview of diabetic neuropathy and its symptoms. She then explains the pathogenesis of diabetic neuropathy related to oxidative stress and the various pathways involved. Angela presents a study that evaluated the effects and safety of ALA in diabetic peripheral neuropathy. The study found that ALA significantly improved median and peroneal nerve conduction velocities in the treatment group compared to the control group. No serious adverse events were observed. She also discusses the safety profile of ALA and its potential benefits in improving insulin sensitivity. Angela concludes by highlighting the limitations of the study and the need for further research to assess the objective improvement in nerve conduction velocities.

Keywords

transverse myelitis

neuromuscular electrical stimulation

muscle weakness

journal article

diabetic peripheral neuropathy

nerve conduction velocities

safety profile

insulin sensitivity