February 2025 CME Activity: Prevalence and Clinical Implications of Osteosarcopenia in Patients With Acute Stroke A Cross-sectional Study-Prevalence and Clinical Implications of Osteosarcopenia in Patients With Acute Stroke A Cross-sectional Study

Prevalence and Clinical Implications of Osteosarcopenia in Patients With Acute Stroke A Cross-sectional Study

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This study aims to assess the prevalence of osteosarcopenia—simultaneous occurrence of osteoporosis and sarcopenia—in acute stroke patients. Conducted by Kyoung Tae Kim and colleagues, this cross-sectional study involved 224 patients within two weeks of experiencing a stroke. Researchers measured various demographic, functional, and clinical metrics including handgrip strength, body composition via DXA, and stroke severity scales to examine muscle and bone loss. <br /><br />Findings revealed that 28.6% of the patients had osteosarcopenia, with osteosarcopenia patients having notably higher stroke severity and more disabilities compared to others. The study identified older age, female sex, and lower body mass index as significant risk factors for developing osteosarcopenia. The study also noted a strong prevalence of these complications in females and in patients aged 65 and older. The overall prevalence of osteoporosis was 46.9%, and sarcopenia 50.9%, with significant prevalence in women. These conditions exacerbate stroke-related disabilities due to increased risks of falls and fractures.<br /><br />Interestingly, the study noted that after stroke, the rapid muscle and bone loss exacerbates, highlighting the need for early diagnosis to implement optimal rehabilitation strategies. Age was a strong factor, with the study citing a cutoff age of 76.5 years for screening osteosarcopenia in stroke patients. <br /><br />The findings suggest that due to the aging population, osteosarcopenia will become more prevalent, necessitating integrated approaches to treatment and rehabilitation to mitigate its impact on stroke patients' quality of life. The study underscores the need for a coordinated diagnostic and therapeutic approach to manage the dual complications of osteoporosis and sarcopenia in stroke recovery.

Keywords

osteosarcopenia

acute stroke

osteoporosis

sarcopenia

prevalence

risk factors

rehabilitation

aging population

bone loss

muscle loss